FREE SAMPLE QUESTIONS

NPTE Pathology Practice Questions (330 Flashcards)

Preparing for the NPTE (National Physical Therapy Examination) exam? Pathology is one of the areas our deck drills hardest: 330 of its 1010 flashcards focus on pathology, covering topics like SBP, Ischemic Heart Disease. Try the sample questions below — every card is a real question-and-answer pair from the full deck.

330

Cards on this topic

1010

Total NPTE cards

$7

Full access

Sample NPTE Practice Questions

Question 1

A 62-year-old male with stable angina experiences chest pain during treadmill walking at 4 METs. Pain subsides after 3 minutes of rest. What is the most likely pathophysiological cause of this transient ischemia?

Show answer →
Answer

Stable angina is caused by a fixed atherosclerotic narrowing of coronary arteries. Ischemia occurs when myocardial oxygen demand (MVO2) exceeds supply. **NPTE Key:** Stable angina is predictable, triggered by specific exertion levels, and relieved by rest or nitroglycerin. **Strategy:** Distinguish from unstable angina, which occurs at rest or with decreasing thresholds. If pain persists >15-20 mins despite rest, suspect Myocardial Infarction (MI).

Question 2

A patient post-MI shows ST-segment elevation in leads V3 and V4 during an EKG screen. Which coronary artery is most likely occluded, and which area of the heart is affected?

Show answer →
Answer

ST elevation in V3-V4 indicates an **Anterior Wall MI**, typically involving the **Left Anterior Descending (LAD)** artery. **Clinical Pearl:** The LAD is often called the widow maker due to its role in supplying the left ventricle. **FSBPT Focus:** V1-V2 (Septal), V3-V4 (Anterior), V5-V6, I, aVL (Lateral), II, III, aVF (Inferior/RCA). Understanding localization helps predict complications like heart failure (LAD) or bradycardia/conduction blocks (RCA).

Question 3

During Phase I cardiac rehab, a patient 3 days post-STEMI exhibits a drop in systolic blood pressure (SBP) of 15 mmHg with low-level activity. What is the appropriate PT action and the underlying concern?

Show answer →
Answer

**Action:** Terminate exercise immediately and notify medical staff. **Rationale:** A drop in SBP >10 mmHg during exercise is an absolute termination criterion. It suggests pump failure or severe ischemia. **NPTE Strategy:** Normal response is a rise in SBP (approx. 10 mmHg per MET). A flat or falling SBP (exertional hypotension) is a red flag for significant LV dysfunction or multi-vessel CAD. Differentiate from orthostatic hypotension, which occurs only during position changes.

Question 4

A patient 4 days post-MI suddenly develops a new, loud holosystolic murmur heard best at the apex, accompanied by acute respiratory distress. What complication should the PT suspect?

Show answer →
Answer

**Acute Mitral Regurgitation** due to **Papillary Muscle Rupture**. This is a medical emergency occurring 2-7 days post-MI. **Clinical Reasoning:** The mitral valve fails, causing backflow into the left atrium and pulmonary edema. **Distractor Alert:** Ventricular Septal Defect (VSD) also causes a holosystolic murmur but is usually heard at the left sternal border. Both require immediate cessation of PT and emergency surgical consult.

Question 5

How does the long-term use of Beta-Blockers (e.g., Metoprolol) influence the exercise prescription for a patient with Ischemic Heart Disease?

Show answer →
Answer

Beta-blockers decrease HR and BP at rest and during exercise by blocking sympathetic input. **PT Impact:** Blunted HR response makes age-predicted Max HR formulas (220-age) invalid for intensity calculation. **Management:** Use the **Rating of Perceived Exertion (RPE)** (target 11-13 on Borg 6-20 scale) for intensity monitoring. **NPTE Strategy:** If a question mentions beta-blockers, RPE is almost always the correct answer for monitoring intensity.

325+ more pathology cards in the full deck

Unlock all 1010 NPTE flashcards — one-time $7, lifetime access, no subscription.

Frequently Asked Questions

How many NPTE pathology practice questions are in the deck?

The full NPTE deck contains 1010 flashcards, and 330 of them focus on pathology. This page shows 5 free samples.

How important is pathology for the NPTE exam?

Our NPTE deck dedicates 330 of 1010 cards (33%) to pathology — always cross-check the official FSBPT exam outline for the current blueprint weighting.

Can I study these pathology flashcards for free?

Yes — the samples on this page are free, and the NPTE preview page has 30 more free cards. Full access to all 1010 cards is a one-time $7.